EHI Peer-Reviewed Journal Publications (Year 2010-2013)

2013

1. Lee, R.C., Hapuarachchi, H.C., Chen, K.C., Hussain, K.M., Chen, H., Low, S.L., Ng, L.C., Lin, R., Ng, M.M., Chu, J.J. (2013). Mosquito cellular factors and functions in mediating the infectious entry of chikungunya virus. PLoS Neglected Tropical Diseases;7(2): e2050. [Full Text]
2. Hapuarachchi, H.C., Oh, H.M., Thein, T.L., Pok, K.Y., Lai, Y.L., Tan, L.K., Lee, K.S., Leo, Y.S., Ng, L.C. (2013). Clinico-genetic characterisation of an encephalitic dengue virus 4 associated with multi-organ involvement. Journal of Clinical Virology; 57(1): 91-94. [Full Text]
3. Lee, C., Vythilingam, I., Chong, C.S., Abdul Razak, M.A., Tan, C.H., Liew, C., Pok, K.Y., Ng, L.C. (2013).Gravitraps for the management of dengue clusters in Singapore. American Journal of Tropical Medicine & Hygiene;88(5): 888-892. [Full Text]
4. Chan, M., Lin, L., Yap, G., Ng, L.C., Leo, Y.S. (2013).Haemorrhagic fever with renal syndrome, Singapore. Annals Academy of Medicine Singapore; 42(5): 257-258. [PDF]
5. Yap, G., Li, C., Mutalib, A., Lai, Y.L., Ng, L.C. (2013).High rates of inapparent dengue in older adults in Singapore.American Journal of Tropical Medicine & Hygiene; 88(6): 1065-1069. [Full Text]
6. Tan, L.K., Lim, S., Low, S.L., Tan, F.H., Ng, L.C., Teo, D. (2013).Evaluation of pathogen reduction systems to inactivate dengue and chikungunya viruses in apheresis platelets suspended in plasma. Advances in Infectious Diseases;3(1): 1-9. [PDF]
7. Wong, P.S.J., Li, M.Z.I., Chong, C.S., Ng, L.C., Tan, C.H. (2013).Aedes (Stegomyia) albopictus (Skuse): a potential vector of Zika virus in Singapore. PLoS Neglected Tropical Diseases;7(8): e2348.[Full Text]
8. Koo, C., Nasir A., Hapuarachchi H.C., Lee K.S., Hasan Z., Ng, L.C., Khan, E. (2013). Evolution and heterogeneity of multiple serotypes of dengue virus in Pakistan, 2006-2011. Virology Journal;10: 275. [Full Text]
9. Cranston, P.S., Ang, Y.C., Heyzer, A., Lim, R.B.H., Wong, W.H., Woodford, J.M., Meier, R. (2013). The nuisance midges (Diptera: Chironomidae) of Singapore's Pandan and Bedok reservoirs. The Raffles Bulletin of Zoology; 61(2): 779-793. [PDF]
10. Leo, Y.S., Gan, V., Ng, E.L., Hao, Y., Ng, L.C., Pok, K.Y., Dimatatac, F. (2013). Utility of warning signs in guiding admission and predicting severe disease in adult dengue. BMC Infectious Diseases; 13: 498. [Full Text]
11. Wilder-Smith, A., Earnest, A., Ma, S., Ng, LC. (2013). Haze and dengue: the unanswered questions. Annals, Academy of Medicine;42(12): 687-688.[PDF]
12. Ng, L.C., Ho, D. (2013). Challenges of Dengue control. Annals, Academy of Medicine; 42(12): 696-697. [PDF]

2012

1. Ng, L.C., Vythilingam, I. (2012).Vectors of Flaviviruses and Strategies for Control. Chapter 15 of Molecular Virology and Control of Flaviviruses. Editor: Pei-Yong Shi. Caister Academic Press ISBN: 978-1-904455-92-9.[Link]
2. Lu, D., Koou, S.Y., Png, A.B., Ng, L.C., Phua, S.G. (2012). A novel mosquito feeding system for routine blood-feeding of Aedes aegypti and Aedes albopictus. Tropical Biomedicine; 29(1): 169-174. [PDF]
3. Cheong, M.S., Ho, J.S., Tan, C.H., Wong, P.S., Ng, L.C., Toh, C.S. (2012). Development of an electrochemical membrane-based nanobiosensor for ultrasensitive detection of dengue virus. Analytica Chimica Acta; 725: 74-80. [Link]
4. Li, M.Z., Wong, P.S., Ng, L.C., Tan, C.H. (2012).Oral susceptibility of Singapore Aedes (Stegomyia) aegypti (Linnaeus) to Zika virus. PLoS Neglected Tropical Diseases;6(8): e1792.[Full Text]
5. Rai, V., Hapuarachchi, H.C., Ng, L.C., Soh, S.H., Leo, Y.S., Toh, C.S. (2012). Ultrasensitive cDNA detection of dengue virus RNA using electrochemical nanoporous membrane-based biosensor. PLoS ONE; 7(8): e42346. [Full Text]
6. Lee, R.M., Phua, S.G., Tan, W.C., Pang, S.C., Vythilingam, I., Ng, L.C., Rueda, L.M. (2012). Mosquito fauna of Ubin island, Singapore. Journal of the American Mosquito Control Association;28(3): 248-254. [PDF]
7. Lee, V.J., Chow, A., Zheng, X., Carrasco, L.R., Cook, A.R., Lye, D.C., Ng, L.C., Leo, Y.S. (2012). Simple clinical and laboratory predictors of chikungunya versus dengue infections in adults. PLoS Neglected Tropical Diseases;6(9): e1786. [Full Text]
8. Hii, Y.L., Rocklöv, J., Wall, S., Ng, L.C., Tang, C.S., Ng, N. (2012). Optimal lead time for dengue forecast. PLoS Neglected Tropical Diseases;6(10): e1848. [Full Text]
9. Hii, Y.L., Zhu, H., Ng, N., Ng, L.C., Rocklöv, J. (2012) Forecast of dengue incidence using temperature and rainfall. PLoS Neglected Tropical Diseases;6(11): e1908. [Full Text]
10. Lee, K.S., Lo, S., Tan, S.S.Y., Chua, R., Tan, L.K., Xu, H., Ng, L.C. (2012).Dengue virus surveillance in Singapore reveals high viral diversity through multiple introductions and in situ evolution. Infection, Genetics and Evolution;12(1): 77-85. [Link]

2011

1. Tan, C. H., Wong, P.S., Li, M.Z., Vythilingam, I., Ng, L.C. (2011). Evaluation of the dengue NS1 Ag Strip® for detection of dengue virus antigen in Aedes aegypti (Diptera: Culicidae). Vector-Borne and Zoonotic Diseases; 11(6): 789-792. [PDF]
2. Sumanadasa, S.D.M., Lee, C., Lam-Phua, S.G., Lu, D., Chiang, L.P., Koou, S.Y., Tan, C.H., Pang, S.C., Maideen, N., Ng, L.C., Vythilingam, I. (2011). Misting of Bacillus thuringiensis israelensis (Bti) to control Aedes albopictus in an industrial area – the Singapore experience. Dengue Bulletin; 35: 181-193. [PDF]
3. Yap, G., Kumar, S.B., Ng, L.C. (2011) Use of saliva for early dengue diagnosis. PLoS Neglected Tropical Diseases;5(5): e1046. [PDF]
4. Ler, T.S., Ng, L.C., Yap, G., Ang, L.W., Tai, J.C., James, L., Goh, K.T. (2011).Epidemiological characteristics of the 2005 and 2007 dengue epidemics in Singapore - similarities and distinctions. Western Pacific Surveillance and Response;2(2): 24-29.[Full Text]
5. Tan, C.H., Wong, P.S., Li, M.Z., Tan, S., Lee, T.K., Pang, S.C., Phua, S.G., Nasir, M., Png, A.B., Koou, S.Y., Deng, L.,Ng, L.C. (2011). Entomological investigation and control of a chikungunya cluster in Singapore. Vector Borne and Zoonotic Diseases 11(4): 383-390. [PDF]
6. Lim, Y.H., Kek, R., Lim, P.Y., Yap, J., Goh, V., Ng, L.C. (2011) Environmental surveillance and molecular characterization of Legionella in tropical Singapore. Tropical Biomedicine;28(1): 149-159. [PDF]
7. Ng, L.C. (2011).Challenges in dengue surveillance and control in the Western Pacific region. Editorial in Western Pacific Surveillance and Response Journal;2(2): 1-3. [Full Text]
8. Kasai, S., Ng, L.C., Lam-Phua, S.G., Tang, C.S., Itokawa, K., Komagata, O., Kobayashi, M., Tomita, T. (2011). First detection of a putative knockdown resistance gene in major mosquito vector, Aedes albopictus. Japanese Journal of Infectious Diseases;64: 217–221. [PDF]
9. Low, J., Ong, A., Tan, L.K., Chaterji, S., Chow, A., Lim, W.Y., Lee, K.W., Chua, R., Tan, W.S., Cheung, Y.B., Hibberd, M., Vasudevan, S., Ng, L.C., Leo, Y.S., Ooi. E.E. (2011). The early clinical features of dengue in adults: challenges for early clinical diagnosis. PLoS Neglected Tropical Diseases; 5(5): e1191. [PDF]
10. Jackson, S. T., Chu, J., Chia, P. Y., Morgan, O. S. C. & Ng, L.C. (2011). Dengue Encephalitis. Flavivirus Encephalitis, Daniel Ruzek (Editor). InTech Open Access Publisher ISBN 978-953-307-669-0 [Link]
11.  Wong, P.S., Tan, C.H., Lee, V., Li, M.Z., Lee, K.S., Lee, P.J., Singh. B., Ng, L.C. (2011). Molecular epidemiological investigation of Plasmodium knowlesi in humans and macaques in Singapore. Vector-Borne and Zoonotic Diseases; 11(2): 131-135. [PDF] 
12. Rai, V., Nyine, Y.T., Hapuarachchi, H.C., Yap, H.M., Ng, L.C., Li, S.F.Y., Toh, C.S. (2011). Electrochemically amplified molecular beacon biosensor for ultrasensitive DNA sequence-specific detection of Legionella sp. Biosensors and Bioelectronics; 32(1): 133-140. [Full Text]
13. Carrasco, L.R., Lee, L.K, Lee, V.J., Ooi, E.E., Shepard, D.S., Thein, T.L., Gan, V., Cook, A.R., Lye, D., Ng, L.C., Leo, Y.S. (2011). Economic impact of dengue illness and the cost effectiveness of future vaccination programs in Singapore. PLoS Neglected Tropical Diseases; 5(12): e1426. [Full Text]
14. Leo, Y.S., Ng, L.C., Cutter, J. (2011).Dengue research in Singapore marking the inaugural ASEAN Dengue Day.Annals Academy of Medicine Singapore;40(12): 520-523. [PDF] 
15. Lam, S.K., Burke, D., Capeding, M.R., Chong, C.K., Coudeville, L., Farrar, J., Gubler, D., Hadinegoro, S.R., Hanna, J., Lang, J., Lee, H.L., Leo, Y.S., Luong, C.Q., Mahoney, R., McBride, J., Mendez-Galvan, J., Ng, L.C., Nimmannitya, S., Ooi, E.E., Shepard, D., Smit, J., Teyssou, R., Thomas, L., Torresi, J., Vasconcelos, P., Wirawan, D.N., Yoksan, S. (2011). Preparing for introduction of a dengue vaccine: recommendations from the 1st Dengue v2V Asia-Pacific Meeting. Vaccine; 29(51): 9417-9422. [Full Text]
16. Zarowieck, M., Walton, C., Torres, E., McAlister, E., Htun, P.T., Sumrandee, C., Sochanta, T., Dinh, T.H., Ng, L.C., Linton, Y.M. (2011). Pleistocene genetic connectivity in a widespread, open-habitat-adapted mosquito in the Indo-Oriental region. Journal of Biogeography; 38(7): 1422-1432. [Full Text]

2010

1. Lee, K.S., Lai, Y.L., Lo, S., Barkham, T, Aw, P., Ooi, P.L., Tai, J.C., Hibberd, M., Johansson, P., Khoo, S.P., Ng, L.C.(2010). Dengue virus surveillance for early warning, Singapore. Emerging Infectious Diseases; 16(5): 847-849. [PDF]
2. Ooi, E.E., Wilder-Smith, A., Ng, L.C., Gubler, D.J. (2010). The 2007 dengue outbreak in Singapore. Epidemiology and Infection;138(7): 958-959. [Link]
3. Jeffery, J., Lee, R., Tan, S.Y., Ng, L.C., Lam-Phua, S.G. (2010). New mosquito species records (Diptera: Culicidae) from Singapore. Tropical Biomedicine;27(1): 138–142. [PDF]
4. Pursem, V.N., Barkham. T., Ng, L.C., Inoue, M., Manraj, S.S. (2010). Re-emergence of dengue in Mauritius. 2010. Emerging Infectious Diseases;16(4): 716-718. [PDF]
5. Lee, V., Ow, S., Heah, H., Tan, M.Y., Lam, P., Ng, L.C., Lam-Phua, S.G., Qadir, A., Seet, B. (2010). Elimination of mosquito-borne disease risk through integrated combination strategies in a tropical military training island. American Journal of Tropical Medicine and Hygiene; 82(6): 1024-1029. [PDF]
6. Yap, G., Pok, K.Y., Lai, Y.L., Hapuarachchi, H.C., Chow, A., Leo, Y.S., Tan, L.K., Ng, L.C. (2010). Evaluation of chikungunya diagnostic assays: differences in sensitivity of serology assays in two independent outbreaks. PLoS Neglected Tropical Diseases;4(7): e753. [PDF]
7. Ng, L.C., Hapuarachchi, H.C. (2010). Tracing the path of chikungunya virus – evolution and adaptation. Infection, Genetics and Evolution;10(7): 876-885. [Full Text]
8. Ng, L.C., Lee, K.S., Tan, C.H., Ooi, P.L., Phua, S.G., Lin, R., Pang, S.C., Lai, Y.L., Solhan, S., Chan, P.P., Wong, K.Y., Ho, S.T., Vythilingam, I. (2010). Entomologic and molecular investigation into Plasmodium vivax transmission in Singapore, 2009. Malaria Journal; 9: 305. [PDF]
9. Vythilingam, I. (2010). Plasmodium knowlesi in humans: a review on the role of its vectors in Malaysia. Tropical Biomedicine; 27(1): 1-12. [PDF]
10. Hapuarachchi, H.C., Bandara, K.B.A.T., Sumanadasa, S.D.M., Hapugoda, M.D., Lai, Y.L., Lee, K.S., Tan, L.K., Lin, R.T.P., Ng, L.F.P., Bucht, G., Abeyewickreme, W., Ng, L.C. (2010).Re-emergence of chikungunya virus in South-east Asia: virologic evidence from Sri Lanka and Singapore. Journal of General Virology; 91: 1067-1076. [PDF]
11. Johansson, P., Yap, G., Low, H.T., Siew, C.C., Kek, R., Ng, L.C., Bucht, G. (2010). Molecular characterisation of two hantavirus strains from different rattus species in Singapore. Virology Journal; 2(7): 15. [PDF]
12. Pok, K.Y., Lai, Y.L., Sng, J., Ng, L.C. (2010). Evaluation of nonstructural 1 antigen assays for the diagnosis and surveillance of dengue in Singapore. Vector-Borne and Zoonotic Diseases; 10(10): 1009-1016. [PDF]